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Games like Pathogenic

2026PCSteam Deck verified9.99 €

A roguelike shooter where you play as a pathogen invading the human body, evolving your parasite with collected organelles. You fight the host's immune system across procedurally generated microscopic environments.

  • Runs that play out differently every time
  • Shooting and gunplay
  • Strong character progression
  • Action-packed real-time combat
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Buy from 9.99 €
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More in these topics: Roguelikes and roguelites Action games

The closest matches for Pathogenic are Deep Rock Galactic: Survivor, Juicy Realm and Deadlink. Each of these 10 games shares something of what makes Pathogenic special – the reasons are listed right on each game.

10 games with a similar feel, sorted by match

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Best match

Deep Rock Galactic: Survivor

92 %Match

2025PCPlayStationXboxNintendo SwitchSteam Deck verified87 % positive12.99 €

  • Runs that play out differently every time
  • Shooting and gunplay
  • Strong character progression

A survivor-like set in the Deep Rock universe where a lone dwarf auto-shoots through alien swarms while carving through destructible rock for minerals. Synergizing weapon upgrades and persistent unlocks deliver that one-more-run pull.

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Buy from 12.99 €
Steam

Juicy Realm

Action-packed real-time combat

A fast top-down roguelike shooter where you play a soldier blasting through randomized levels full of mutated, hostile fruit. Plenty of weapons, upgrades and a bright, cartoonish look make for quick, varied runs.

Deadlink

Runs that play out differently every time

A fast cyberpunk first-person shooter with roguelite structure where you pilot a remote combat shell through corporate strongholds. Fluid movement, destructible environments and upgrades between runs drive the pace and replayability.

Starward Rogue

Action-packed real-time combat

A roguelite bullet-hell shooter where you fight through randomly generated labyrinths inside a star, weaving through waves of projectiles while collecting weapons and upgrades. Each run feels different thanks to varied item combinations.

Beacon

Runs that play out differently every time

Beacon is a top-down sci-fi shooter where you fight through a randomly generated hostile planet to find your distress beacon. Each death lets you recombine DNA harvested from enemies, so every run makes your next attempt stronger.

Galactic Glitch

Runs that play out differently every time

A roguelike shooter built around physics: hurl rocks, catch missiles and turn torn-apart enemies into ammo. You craft your own build from many weapons and powers while exploring a simulated universe.

Drifting Lands

Runs that play out differently every time

A side-scrolling shoot-'em-up blended with the loot, builds and skill trees of hack & slash games. Between missions you tune and rebuild your ship for the next run.

Galak-Z: The Dimensional

Timing and reflexes matter (parrying, dodging)

A punchy 2D space shooter with physics-driven flight, roguelike structure and a look inspired by 80s mecha anime. Intense dogfights demand quick reflexes and smart resource management.

Void/Breaker

Runs that play out differently every time

A fast-paced roguelite first-person shooter where you fight machines controlled by a hostile AI. Deep gun modding and build synergies make every run feel different.

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