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Cover of Trauma Center: Second Opinion

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Games like Trauma Center: Second Opinion

2006

You play surgeon Derek Stiles in a near-future hospital where every operation becomes a tense, timed puzzle. Between the procedures, a mysterious outbreak slowly unfolds into a gripping medical story.

  • Puzzles and brain teasers
  • Strong, story-driven narrative
  • Sci-fi setting
  • Challenging difficulty
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More in these topics: Puzzle games

The closest matches for Trauma Center: Second Opinion are Cyberia, The Turing Test and The Entropy Centre. Each of these 10 games shares something of what makes Trauma Center: Second Opinion special – the reasons are listed right on each game.

10 games with a similar feel, sorted by match

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Best match

Cyberia

84 %Match

1994PCPlayStationSteam Deck playable9.99 €

Brings what grabs you about Trauma Center: Second Opinion: a sci-fi setting, puzzles to figure out and a strong story.

A 90s pre-rendered sci-fi adventure in which you solve puzzles in a secret Russian base and fight rail-shooter-style sequences in a cockpit to stop a world-ending superweapon.

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Steam

The Turing Test

Strong, story-driven narrative

A first-person puzzle game set on Jupiter's moon Europa, where you play engineer Ava Turing solving chambers built on energy and physics puzzles. Along the way it reflects on artificial intelligence, morality and what consciousness really means.

The Entropy Centre

Strong, story-driven narrative

A first-person puzzle game where a time-rewinding gun lets you send objects back through their past to solve clever challenges. It wraps this in a sci-fi mystery set in a strange research facility, with a chatty AI companion.

Exapunks

Challenging difficulty

A programming puzzle game set in a 1990s hacker world, where you write assembly-like scripts for tiny spider-bots that crawl through other people's networks. It pairs a grim cyberpunk story about a deadly virus with a charming zine-style manual.

Relicta

Strong, story-driven narrative

A first-person puzzle game set on a lunar base where you combine magnetism and gravity powers to solve physics challenges and uncover the station's secrets, wrapped in a personal father-daughter story.

TIS-100

Challenging difficulty

A programming puzzler where you write assembly-style code for a broken, fictional computer to fix its nodes. Dry, demanding and all about tinkering and optimizing solutions.

Q.U.B.E.

Linear, curated structure

A first-person puzzle game set in a minimalist world of white cubes, where special gloves let you manipulate coloured blocks. The puzzles rely on physics, timing and spatial thinking.

Causality

Challenging difficulty

In Causality you bend time, reshape the sequence of events within short, hazardous moments, and guide stranded astronauts to matching exits with the help of your past selves. It is a demanding puzzler built around clever time paradoxes on alien landscapes.

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